In a recent study led by Oxford University and published in the London-based medical journal The Lancet, analysed 522 data involving 21 different types of anti-depressants.
The study was aimed to clear doubts over anti-depressants, which has been described by some people as conspiracies of big firms or no more effective than placebos, found that all tested drugs were effective in treating depression.
The lead author Dr. Andrea Cipriani said he was “very excited” about the findings, which he said provided a “final answer” to the controversy over the effectiveness of the drugs.
The study shows that the least common agomelatine, amitriptyline, escitalopram, mirtazapine and paroxetine were the most effective anti-depressants.
Some of the well-known antidepressants such as Prozac, fluoxetine, were among the least effective.
Antidepressants are very effective in treating depression. Untreated depression is a huge burden for patients and their loved ones,” Author – Dr. Andrea Cipriani, (NIHR Oxford Health Biomedical Research Centre).
According to the World Health Organisation (WHO), there are 322 million people living with depression in the world. In the WHO suicide ranking,
With suicide the second leading cause of death among 15 to 29-year-olds. WHO said close to 800 000 people die from suicide annually.
Nigeria, with 15.1 suicides per 100,000 population per year, is ranked the 30th most suicide-prone out of 183 nations in the world and 10th in Africa, alongside Togo (26th in the world), Burkina Faso (22nd), Cameroun (19th) Zimbabwe (16th), Central African Republic (13th), Sierra Leone (11th), Angola (9th), Equatoria Guinea (7th) and Cote D’Ivoire (5th).
The world health body said depression is different from usual mood fluctuations and short-lived emotional responses to challenges in everyday life.
Researchers said Doctors are too easily disgusted in offering medication for depression, but would not hesitate to ensure patients received treatment for cancer or heart disease
The UN organisation also warned that the burden of depression and other mental health conditions is on the rise globally.
A World Health Assembly resolution passed in May 2013 has called for a comprehensive, coordinated response to mental disorders at country level.